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Symbol
Name
ID

Ube3b
ubiquitin protein ligase E3B
MGI:1891295

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Microcephaly	Ventriculomegaly	Hypoplasia of the corpus callosum	Absent speech	Intellectual disability	Intellectual disability, severe	Global developmental delay	Motor delay	Specific learning disability
Disease(s) Associated with UBE3B
Kaufman oculocerebrofacial syndrome

Mouse Phenotypes		nervous system phenotype	decreased brain size	enlarged brain ventricles	abnormal corpus callosum morphology	decreased dentate gyrus size	small hippocampus	abnormal primary somatosensory cortex morphology	abnormal dendrite morphology	decreased dendritic spine density	abnormal synapse morphology
Availability	Mouse Genotype	nervous system phenotype	decreased brain size	enlarged brain ventricles	abnormal corpus callosum morphology	decreased dentate gyrus size	small hippocampus	abnormal primary somatosensory cortex morphology	abnormal dendrite morphology	decreased dendritic spine density	abnormal synapse morphology
	Ube3b^{Gt(RRJ142)Byg}/Ube3b^{Gt(RRJ142)Byg}	*
	Ube3b^{tm1a(EUCOMM)Hmgu}/Ube3b^{tm1a(EUCOMM)Hmgu}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23